From Book News, Inc.
This handbook for medical researchers presents a wide array of in vitro, cellular, and whole animal protocols. Covering electrophysiology, cell biology, animal models, and gene therapy, the book provides step-by-step instructions for incorporating new approaches into research programs. Specific protocols describe new techniques for diagnosis, in vitro methods for the expression and functional analysis of CFTR, novel biochemical and cellular systems for determining the role of mutations, and in vivo protocols to examine how CFTR dysfunction produces multisystem pathology. The book emphasizes the translation of recent scientific advances into clinical solutions.Book News, Inc., Portland, OR

Book Info
Oregon Health Sciences Univ., Portland. Features detailed instructions to ensure successful experimental results, new multidisciplinary techniques, and cutting-edge clinical and laboratory techniques. Outline format. DNLM: Cystic Fibrosis Transmembrane Conductance Regulator--Laboratory Manuals.

Book Description
Cystic Fibrosis: Methods and Protocols consolidates cutting-edge in vitro, cellular, and whole animal laboratory protocols into an indispensable resource. From electrophysiology and cell biology, to animal models and gene therapy, this comprehensive set of methods provides the step-by-step instructions needed for investigators to incorporate new approaches into their research programs. Specific protocols describe new techniques for diagnosis, in vitro methods for the expression and functional analysis of CFTR, novel biochemical and cellular systems to determine how mutations subvert CFTR function, and in vivo protocols to examine how CFTR dysfunction produce multisystem pathology in both human and animal models.