A comprehensive, multidisciplinary resource for the entire radiation oncology team, Gunderson & Tepper’s Clinical Radiation Oncology, 5th Edition, thoroughly covers all aspects of this complex and dynamic field. Concise, templated chapters cover the basic biology of oncologic disease processes as well as updated treatment algorithms, the latest clinical guidelines, and state-of-the-art techniques and modalities. More than 1,000 images―detailed anatomy drawings, radiographic images, and more―provide outstanding visual support for every area of the text.
* Divides content into three distinct sections for quick access to information: Scientific Foundations, Techniques and Modalities, and Disease Sites. Disease Site chapters include overviews summarizing the most important issues and concluding discussions on controversies and problems.

* Features new and expanded content on molecular and cellular biology and its relevance in individualized treatment approaches, stereotactic radiation therapy, radiosurgery, proton therapy, biologic therapy, precision radiation therapy, targeted radiation, dosing guidelines for better quality of life and improved patient outcomes, and more.

* Includes new chapters on Radiation Physics: Particle Therapy, Interventional Radiology, Radiation Therapy in the Elderly, Palliative Care, Quality and Safety, and Immunotherapy with Radiotherapy.

* Provides guidance on single-modality and combined-modality approaches, as well as outcome data including disease control, survival, and treatment tolerance.

* Includes access to videos on Intraoperative Irradiation, Prostate Brachytherapy, Penile Brachytherapy, and Ocular Melanoma.
* Expert Consult™ eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.

Part A. Radiobiology

1. The Biological Basis of Radiation Oncology

2. Molecular and Cellular Biology

3. Dose-Response Modifiers in Radiation Therapy

4. Interaction of Chemotherapy and Radiation

5. Biologics and Their Interactions with Radiation


Part B. Physics

6. Radiation Oncology Physics

7. Radiation Physics - Stereotactic


Part C. Related Cancer Disciplines

8. Surgical Principles

9. Principles of Chemotherapy

10. Imaging in Oncology

11. Nuclear Medicine

12. Health Services Research in Radiation Oncology

13. Statistics and Clinical Trials

14. Late Effects after Radiation


SECTION II TECHNIQUES AND MODALITIES


15. Brachytherapy

16. Intensity-Modulated and Image-Guided Radiation Therapy

17. Intraoperative Irradiation

18. Total Body Irradiation

19. Charged Particle Radiotherapy

20. Neutron Radiotherapy

21. Hyperthermia

22. Targeted Radionuclide Therapy

23. Stereotactic Irradiation: CNS Tumors

24. Stereotactic Body Irradiation: Extracranial Tumors

25. Metastatic Disease: Bone, Spinal Cord, Brain, Liver, and Lung


SECTION III DISEASE SITES


Part A. Central Nervous System Tumors

Overview

26. Low-Grade Gliomas

27. High-Grade Gliomas

28. Benign Brain Tumors: Meningiomas and Vestibular Schwannomas

29. Pituitary Tumors and Craniopharyngiomas

30. Spinal Cord Tumors

31. Orbital, Ocular, and Optic Nerve Tumors


Part B. Head and Neck Tumors

Overview

32. Oral Cavity

33. Oropharyngeal Cancer

34. Nasopharyngeal Carcinoma

35. Larynx and Hypopharynx Cancer

36. Sinonasal Cancer

37. Salivary Gland Malignancies

38. Thyroid Cancer

39. Unknown Head and Neck Primary Site

40. Management of the Neck

41. Cutaneous Carcinoma

42. Malignant Melanoma


Part C. Thoracic Neoplasms

Overview

43. Small Cell Lung Cancer

44. Non-Small Cell Lung Cancer

45. Cancer of the Esophagus

46. Uncommon Thoracic Tumors


Part D. Gastrointestinal Tumors

Overview

47. Gastric/GE Junction Cancer

48. Pancreatic Cancer

49. Hepatobiliary Cancer

50. Colon Cancer

51. Rectal Cancer

52. Anal Carcinoma


Part E. Genitourinary Tumors

Overview

53. Prostate Cancer

54. Bladder Cancer

55. Testicular Cancer

56. Kidney and Ureteral Carcinoma

57. Penile Cancer


Part F. Gynecologic Tumors

Overview

58. Cervical Cancer

59. Endometrial Cancer

60. Cancers of the Vulva and Vagina

61. Ovarian Cancer


Part G. Breast Cancer

Overview

62. Noninvasive Breast Cancer

63. Breast Cancer: Stages I-II

64. Breast Cancer: Postmastectomy Radiation, Locally Advanced Disease, and Inflammatory Breast Cancer


Part H. Sarcoma and Benign Disease

65. Soft Tissue Sarcoma

66. Benign Diseases


Part I. Childhood Cancers

Overview

67. Central Nervous System Tumors

68. Pediatric Soft Tissue Sarcomas

69. Pediatric Sarcomas of Bone

70. Wilms' Tumor

71. Retinoblastoma

72. Neuroblastoma

73. Pediatric Leukemias and Lymphomas

74. Pediatric Hodgkin's Lymphoma

75. Rare Pediatric Tumors


Part J. Lymphoma and Hematologic Malignancies

Overview

76. Hodgkin's Lymphoma

77. Non-Hodgkin's Lymphoma

78. Multiple Myeloma and Other Plasma Cell Neoplasms

79. Mycosis Fungoides

SECTION I SCIENTIFIC FOUNDATIONS OF RADIATION ONCOLOGY


Part A. Radiobiology

1. The Biological Basis of Radiation Oncology

2. Molecular and Cellular Biology

3. Dose-Response Modifiers in Radiation Therapy

4. Interaction of Chemotherapy and Radiation

5. Biologics and Their Interactions with Radiation


Part B. Physics

6. Radiation Oncology Physics

7. Radiation Physics - Stereotactic


Part C. Related Cancer Disciplines

8. Surgical Principles

9. Principles of Chemotherapy

10. Imaging in Oncology

11. Nuclear Medicine

12. Health Services Research in Radiation Oncology

13. Statistics and Clinical Trials

14. Late Effects after Radiation


SECTION II TECHNIQUES AND MODALITIES


15. Brachytherapy

16. Intensity-Modulated and Image-Guided Radiation Therapy

17. Intraoperative Irradiation

18. Total Body Irradiation

19. Charged Particle Radiotherapy

20. Neutron Radiotherapy

21. Hyperthermia

22. Targeted Radionuclide Therapy

23. Stereotactic Irradiation: CNS Tumors

24. Stereotactic Body Irradiation: Extracranial Tumors

25. Metastatic Disease: Bone, Spinal Cord, Brain, Liver, and Lung


SECTION III DISEASE SITES


Part A. Central Nervous System Tumors

Overview

26. Low-Grade Gliomas

27. High-Grade Gliomas

28. Benign Brain Tumors: Meningiomas and Vestibular Schwannomas

29. Pituitary Tumors and Craniopharyngiomas

30. Spinal Cord Tumors

31. Orbital, Ocular, and Optic Nerve Tumors


Part B. Head and Neck Tumors

Overview

32. Oral Cavity

33. Oropharyngeal Cancer

34. Nasopharyngeal Carcinoma

35. Larynx and Hypopharynx Cancer

36. Sinonasal Cancer

37. Salivary Gland Malignancies

38. Thyroid Cancer

39. Unknown Head and Neck Primary Site

40. Management of the Neck

41. Cutaneous Carcinoma

42. Malignant Melanoma


Part C. Thoracic Neoplasms

Overview

43. Small Cell Lung Cancer

44. Non-Small Cell Lung Cancer

45. Cancer of the Esophagus

46. Uncommon Thoracic Tumors


Part D. Gastrointestinal Tumors

Overview

47. Gastric/GE Junction Cancer

48. Pancreatic Cancer

49. Hepatobiliary Cancer

50. Colon Cancer

51. Rectal Cancer

52. Anal Carcinoma


Part E. Genitourinary Tumors

Overview

53. Prostate Cancer

54. Bladder Cancer

55. Testicular Cancer

56. Kidney and Ureteral Carcinoma

57. Penile Cancer


Part F. Gynecologic Tumors

Overview

58. Cervical Cancer

59. Endometrial Cancer

60. Cancers of the Vulva and Vagina

61. Ovarian Cancer


Part G. Breast Cancer

Overview

62. Noninvasive Breast Cancer

63. Breast Cancer: Stages I-II

64. Breast Cancer: Postmastectomy Radiation, Locally Advanced Disease, and Inflammatory Breast Cancer


Part H. Sarcoma and Benign Disease

65. Soft Tissue Sarcoma

66. Benign Diseases


Part I. Childhood Cancers

Overview

67. Central Nervous System Tumors

68. Pediatric Soft Tissue Sarcomas

69. Pediatric Sarcomas of Bone

70. Wilms' Tumor

71. Retinoblastoma

72. Neuroblastoma

73. Pediatric Leukemias and Lymphomas

74. Pediatric Hodgkin's Lymphoma

75. Rare Pediatric Tumors


Part J. Lymphoma and Hematologic Malignancies

Overview

76. Hodgkin's Lymphoma

77. Non-Hodgkin's Lymphoma

78. Multiple Myeloma and Other Plasma Cell Neoplasms

79. Mycosis Fungoides