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Cancer Biology, 2th Edition |
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Preface Dedication Acknowledgements 1 What is Cancer? 1 2 Natural History: The Life of a Cancer 8 3 Pathology: Defining a Neoplasm 27 4 Epidemiology: Identifying Causes of Human Cancers 33 5 Tumour Immunology and Immunotherapy 51 6 Oncogenes, Repressor Genes and Viruses 62 7 Chemical and Radiation Carcinogenesis 81 8 Genetic Instability and DNA Repair 104 9 Familial Cancers 115 10 Growth: A Balance of Proliferation, Death and Differentiation 123 11 Responding to the Environment: Growth Regulation and Signal Transduction 141 12 Invasion and Metastasis 165 13 Principles of Cancer Treatment 183 Further Reading 212 Glossary 217
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