Get the authoritative, up-to-date information you need on liver disease from the 7th Edition of the most trusted reference worldwide. Covering both basic science and recent clinical developments, this revised edition by Drs. Arun J. Sanyal, Thomas D. Boyer, Norah A. Terrault, and Keith D. Lindor, provides an in-depth, comprehensive look at the pathophysiology, diagnostic, and treatment information related to the liver. More than 1,100 figures and tables, many new and in full color, highlight completely updated content throughout.


Key Features
- Expert, international authorship and comprehensive, easy-to-access information makes this edition the gold standard in the field of hepatology.

- Expert Consult™ eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, videos, and references from the book on a variety of devices.

Section I. Basics

1. Anatomy and Cellular Functions of the Liver

2. Bile Acids and Bile Flow: New Functions of Old Molecules

3. Intestinal Microbiome and the Liver

4. Liver as an Immune Organ

5. Liver's Response to Injury: Inflammation and Fibrosis

6. Stem Cells and Hepatocyte Transplantation

Section II. Management and Assessment of Liver Disease

7. Approach to Jaundice and Abnormal Liver Function Tests

8. Noninvasive Assessment of Disease Progression

9. Molecular and Genetics-Based Diagnostics

10. Imaging in Assessment of Liver Disease and Lesions

11. Evaluation of the Hepatic Mass

12. Assessment of Liver Histology

13. Critical Care Management of Patients with Liver Disease

Section III. Clinical Consequences of Chronic Liver Disease

14. Neurologic Consequences of Liver Disease

15. Ascites and Hyponatremia

16. Portal Hypertension Related to Bleeding

17. Renal Failure in Cirrhosis

18. Cardiopulmonary Complications of Cirrhosis

19. The Hemostatic and Hematopoietic System in Liver Disease

20. Acute Liver Failure

21. Acute-on-Chronic Liver Failure

Section IV. Specific Diseases

22. Epidemiology and Pathogenesis of Alcoholic Liver Disease

23. Natural History and Cofactors of Alcoholic Liver Disease

24. Prevention and Management of Alcoholic Liver Disease

25. Pathogenesis of Nonalcoholic Fatty Liver Disease

26. Epidemiology, Natural History, and Diagnosis of Nonalcoholic Fatty Liver Disease

27. Management of NAFL-NASH and Metabolic Syndrome

28. Virology and Pathogenesis of Hepatitis C

29. Epidemiology, Natural History, and Diagnosis of Hepatitis C

30. Treatment of Hepatitis C

31. Virology and Pathogenesis of Hepatitis B

32. Epidemiology, Natural History, and Diagnosis of Hepatitis B

33. Treatment of Hepatitis B

34. Hepatitis D

35. Hepatitis A

36. Hepatitis E

Section V. Liver and Other Infections

37. HIV and the Liver

38. Liver Disease Associated with Systemic Viral Infection

39. Parasitic Liver Disease

40. Bacterial and Miscellaneous Infections of the Liver

Section VI. Immune Diseases of the Liver

41. Autoimmune Hepatitis and Overlap Syndrome

42. Primary Biliary Cirrhosis

43. Primary and Secondary Sclerosing Cholangitis

Section VII. Vascular Diseases of the Liver

44. Budd-Chiari and Sinusoidal Obstruction Syndrome

45. Portal and Splenic Vein Thrombosis

Section VIII. Tumors of the Liver

46. Hepatocellular Carcinoma

47. Cholangiocarcinoma

48. Other Malignant Hepatic Tumors

49. Benign Liver Tumors

Section IX. Liver Transplantation

50. Pretransplant Evaluation and Care

51. Transplantation of the Liver

52. Post Liver Transplant Management

53. Recurrent Primary Disease after Transplantation

Section X. Liver Affected by Other Conditions or Diseases

54. Liver and Pregnancy

55. Nutrition and the Liver

56. Drug-Induced Liver Injury

57. Preoperative and Postoperative Hepatic Dysfunction

Section XI. Inherited and Pediatric Liver Diseases

58. Bilirubin Metabolism and Its Disorders

59. Wilson Disease

60. Hemochromatosis

61. Alpha-1 Antitrypsin Deficiency

62. Approach to and Evaluation of Metabolic Liver Diseases

63. Pediatric Cholestatic Syndromes

64. Fibrocystic Diseases of the Liver

65. Viral Hepatitis in Children