The world's leading reference in hematopathology returns with this completely updated second edition. Authored by international experts in the field it covers a broad range of hematologic disorders - both benign and malignant - with information on the pathogenesis clinical and pathologic diagnosis and treatment for each. Comprehensive in scope it's a must-have resource for both residents and practicing pathologists alike.


　New to this edition
　　　ㆍ　Boasts detailed, practical advice from world leaders in hematopathology.
　　　ㆍ　Places an emphasis on pathologic diagnoses, including molecular and genetic testing.
　　　ㆍ　Updated with the most current WHO classifications of hematologic disease, including lymphoma and leukemia and peripheral T-cell lymphomas.
　　　ㆍ　Covers hot topics in hematopathology, such as the latest genetic insights into lymphoma and leukemia; the new nomenclature for myelodysplastic syndromes; new developments on the subject of Grey zone lymphoma; and much more.
　　　ㆍ　Expert Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, images, and references from the book on a variety of devices. There's also a downloadable image bank, and Virtual Microscope Slides are featured in several chapters.


　Key Features
　　　ㆍ　Authored by the chief architects of the WHO classification in neoplasms of hematopoietic and lymphoid tissue.
　　　ㆍ　Covers the newest diagnostic techniques, including molecular, immunohistochemical, and genetic studies.
　　　ㆍ　Confirm or challenge your diagnostic interpretations by comparing specimens to over 1,000 high-quality color images.

Part I: TECHNICAL ASPECTS
　　　─　1. Processing of the Lymph Node Biopsy Specimen 　　
　　　─　2. Fine Needle Aspiration of Lymph Nodes 　　
　　　─　3. Collection, Processing, and Examination of Bone Marrow Specimens
　　　─　4. Immunohistochemistry for the Hematopathology Laboratory
　　　─　5. Flow Cytometry 　　
　　　─　6. Molecular Diagnosis in Hematopathology
　　　─　7. Important Chromosomal Aberrations in Hematologic Neoplasms and Key Techniques to Diagnose Them　　


Part II: NORMAL and REACTIVE CONDTIONS of HEMATOPOIETIC TISSUES
　　　─　8. Normal Lymphoid Organs and Tissues
　　　─　9. The Reactive Lymphadenopathies
　　　─　10. The Normal Bone Marrow
　　　─　11. Evaluation of Anemia, Leukopenia, and Thrombocytopenia
　　　─　12. Bone Marrow Findings in Inflammatory, Infectious, and Metabolic Disorders


Part III: LYMPHOID NEOPLASMS
　　　─　13. Principles of Classification of Lymphoid Neoplasms

　Section 1: Mature B-Cell Neoplasms
　　　─　14. Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma and B-Cell Prolymphocytic Leukemia
　　　─　15. Lymphoplasmacytic Lymphoma and Waldenström Macroglobulinemia
　　　─　16. Hairy Cell Leukemia
　　　─　17. Splenic Marginal Zone Lymphoma and Other Small B-Cell Neoplasms in the Spleen　
　　　─　18. Follicular Lymphoma
　　　─　19. Extranodal Marginal Zone Lymphoma: MALT Lymphoma
　　　─　20. Primary Cutaneous B-Cell Lymphomas
　　　─　21. Nodal Marginal Zone Lymphoma
　　　─　22. Mantle Cell Lymphoma
　　　─　23. Diffuse Large B-Cell Lymphoma
　　　─　24. Burkitt Lymphoma and its Mimics
　　　─　25. Plasmablastic Neoplasms Other Than Plasma Cell Myeloma
　　　─　26. Plasma Cell Neoplasms
　　　─　27. Nodular Lymphocyte-Predominant Hodgkin's Lymphoma
　　　─　28. Classical Hodgkin's Lymphoma and Related Lesions
　　　─　29. Virally Associated B-Cell Lymphoproliferative Disease

　Section 2: MATURE T-CELL AND NK-CELL NEOPLASMS
　　　─　30. Virally Associated T-Cell and NK-Cell Neoplasms
　　　─　31. T-Cell and NK-Cell Large Granular Lymphocyte Proliferations
　　　─　32. T-Cell Prolymphocytic Leukemia
　　　─　33. Adult T-Cell Leukemia/Lymphoma
　　　─　34. Hepatosplenic T-Cell Lymphoma
　　　─　35. Peripheral T-Cell Lymphoma, Not Otherwise Specified
　　　─　36. Angioimmunoblastic T-Cell Lymphoma
　　　─　37. Anaplastic Large-Cell Lymphoma, ALK Positive and ALK Negative
　　　─　38. Enteropathy-Associated T-Cell Lymphoma and Other Primary Intestinal T-Cell Lymphomas
　　　─　39. Mycosis Fungoides and Sézary Syndrome
　　　─　40. Primary Cutaneous CD30-Positive T-Cell Lymphoproliferative Disorders
　　　─　41. Primary Cutaneous T-Cell Lymphomas: Rare Subtypes

　Section 3: Precursor B- and T-Cell Neoplasms
　　　─　42. Precursor B- and T-Cell Neoplasms
　　　─　43. Acute Leukemias of Ambiguous Lineage


Part IV: MYELOID NEOPLASMS
　　　─　44. Principles of Classification of Myeloid Neoplasms
　　　─　45. The Myelodysplastic Syndromes
　　　─　46. Acute Myeloid Leukemia
　　　─　47. Myeloproliferative Neoplasms
　　　─　48. Myelodysplastic/Myeloproliferative Neoplasms
　　　─　49. Mastocytosis
　　　─　50. Eosinophilia and Chronic Eosinophilic Leukemia, Including Myeloid/Lymphoid Neoplasms with Eosinophilia and Rearrangement of PDGFRA, PDGFRB, FGFR1, or JAK2
　　　─　51. Blastic Plasmacytoid Dendritic Cell Neoplasm


Part V: HISTIOCYTIC PROLIFERATIONS
　　　─　52. Nonneoplastic Histiocytic Proliferations of Lymph Nodes and Bone Marrow
　　　─　53. Histiocytic and Dendritic Cell Neoplasms Including Langerhans Cell Histiocytosis and Langerhans Cell Sarcoma
　

Part VI: IMMUNODEFICIENCY DISORDERS
　　　─　54. The Pathology of Primary Immunodeficiencies
　　　─　55. Iatrogenic Immunodeficiency-Associated Lymphoproliferative Disorder


Part VII: SITE-SPECIFIC ISSUES in the DIAGNOSIS of LYMPHOMA and LEUKEMIA
　　　─　56. Bone Marrow Evaluation for Lymphoma
　　　─　57. Evaluation of the Bone Marrow After Therapy
　　　─　58. Non-Hematopoietic Neoplasms of the Bone Marrow
　　　─　59. Nonlymphoid Lesions of the Lymph Nodes
　　　─　60. Spleen: Normal Architecture and Neoplastic and Nonneoplastic Lesions
　　　─　61. Diagnosis of Lymphoma in Extranodal Sites Other Than Skin