Clinical case studies have long been recognized as a useful adjunct to problem-based learning and continuing professional development. They emphasize the need for clinical reasoning, integrative thinking, problem-solving, communication, teamwork and self-directed learning – all desirable generic skills for health care professionals. This book is based on the unique autonomic program at the Mayo Clinic, comprising an autonomic laboratory that studies over 4000 patients annually. The authors teach using actual patient material and laboratory recordings to clarify complex autonomic syndromes. Important and common disorders like neurogenic orthostatic hypotension and distal small fiber neuropathy are described in some detail. There are also fascinating uncommon autonomic syndromes described succinctly and clearly. Emphasis is given to clarifying what is real and highlighting those changes that mimic autonomic dysfunction. Providing a broad breadth of coverage with many clinical examples, the book will be of interest to residents and non-specialist practitioners in neurology and cardiology.


Includes over 350 images
Provides simple vignettes for self-testing
Sample cases enable pattern recognition, identification of potential artifacts and test interpretation

Preface
Introduction
Case 1. Probable Lewy body disease
Case 2. Multiple system atrophy: cerebellar type
Case 3. Multiple system atrophy: predominantly parkinsonism
Case 4. Multiple system atrophy: predominantly parkinsonism
Case 5. Pure autonomic failure
Case 6. Pure autonomic failure
Case 7. Acute autonomic ganglionopathy
Case 8. Acute autonomic ganglionopathy
Case 9. Acute autonomic ganglionopathy
Case 10. Acute autonomic ganglionopathy
Case 11. Chronic idiopathic anhidrosis
Case 12. Pseudo chronic idiopathic anhidrosis
Case 13. Amyloidosis
Case 14. Amyloidosis
Case 15. Leprosy
Case 16. Dopamine: beta-hydrogenase deficiency
Case 17. Hereditary sensory and autonomic neuropathy type I
Case 18. Postural orthostatic tachycardia syndrome with hyperadrenergic storms
Case 19. Postural orthostatic tachycardia syndrome
Case 20. Brainstem dysfunction
Case 21. Baroreflex dysfunction
Case 22. Diabetic neuropathy
Case 23. Severe diabetic autonomic neuropathy
Case 24. Complex regional pain syndrome
Case 25. Pseudo-autoimmune autonomic ganglionopathy (median arcuate ligament syndrome)
Case 26. Erythromelalgia
Case 27. Hypothalamic dysfunction
Case 28. Pheochromocytoma
Case 29. Syncope
Case 30. Harlequin's syndrome
Case 31. Ross' syndrome
Case 32. Autoimmune encephalopathy with autonomic manifestations
Vignettes
Index.