Practical and clinically focused, Abeloff’s Clinical Oncology is a trusted medical reference book designed to capture the latest scientific discoveries and their implications for cancer diagnosis and management of cancer in the most accessible manner possible. Abeloff’s equips everyone involved - from radiologists and oncologists to surgeons and nurses - to collaborate effectively and provide the best possible cancer care.






New to This Edition
Stay at the forefront of the latest developments in cancer pharmacology, oncology and healthcare policy, survivorship in cancer, and many other timely topics.
See how the most recent cancer research applies to practice through an increased emphasis on the relevance of new scientific discoveries and modalities within disease chapters.
Streamline clinical decision making with abundant new treatment and diagnostic algorithms as well as concrete management recommendations.
Take advantage of the collective wisdom of preeminent multidisciplinary experts in the field of oncology, including previous Abeloff’s editors John E. Niederhuber, James O. Armitage, and Michael B. Kastan as well as new editors James H. Doroshow from the National Cancer Institute and Joel E. Tepper of Gunderson & Tepper: Clinical Radiation Oncology.
Quickly and effortlessly access the key information you need with the help of an even more user-friendly, streamlined format.
Access the complete contents anytime, anywhere at Expert Consult, and test your mastery of the latest knowledge with 500 online multiple-choice review questions.


Key Features
Select the most appropriate tests and imaging studies for cancer diagnosis and staging of each type of cancer, and manage your patients in the most effective way possible by using all of the latest techniques and approaches in oncology.
Enhance your understanding of complex concepts with a color art program that highlights key points and illustrates relevant scientific and clinical problems.

Part I: Science of Clinical Oncology
Section A. Biology and Cancer

1 Molecular Tools in Cancer Research

2 Intracellular Signaling

3 The Cellular Microenvironment and Metastases

4 Control of the Cell Cycle

5 Cell Life and Death

6 Cancer Immunology

7 Stem Cells, Cell Differentiation, and Cancer

8 Vascular and Interstitital Biology of Tumors



Section B. Genesis of Cancer

9 Environmental Factors

10 DNA Damage Response Pathways and Cancer

11 Viruses and Human Cancer

12 Genetic Factors: Hereditary Cancer Predisposition Syndromes

13 Genetic and Epigenetic Changes in Cancer

14 Immunodeficiency and Cancer



Section C. Diagnosing Cancer

15 Flow Cytometry in Oncologic Diagnosis

16 World Health Organization Classification of Hematologic Malignancies

17 Pathology, Biomarkers, and Molecular Diagnostics

18 Imaging



Section D. Preventing and Treating Cancer

19 Biostatistics and Bioinformatics in Clinical Trials

20 Structures Supporting Cancer Clinical Trials

21 Oncology and Healthcare Policy

22 Use of Epidemiology in Oncology

23 Cancer Prevention, Screening, and Early Detection

24 Nicotine Dependence: Current Treatments and Future Directions

25 Surgical Interventions in Cancer

26 Establishing and Maintaining Vascular Access

27 Basics of Radiation Therapy

28 Therapeutic Targeting of Cancer Cells

29 Cancer Pharmacology

30 Hematopoietic Stem Cell Transplantation

31 Gene Therapy in Oncology

32 Therapeutic Antibodies and Immunologic Conjugates

33 Complementary and Alternative Medicine



Part II: Problems Common to Cancer and its Therapy

Section A. Hematologic Problems and Infections

34 Disorders of Blood Cell Production in Clinical Oncology

35 Diagnosis, Treatment, and Prevention of Cancer-Related Venous Thrombosis

36 Infection in the Patient with Cancer



Section B. Metabolic and Paraneoplastic Syndromes

37 Hypercalcemia

38 Tumor Lysis Syndrome

39 Paraneoplastic Neurologic Syndromes

40 Cancer Pain

41 Cachexia

42 Nausea and Vomiting

43 Oral Complications

44 Alopecia and Cutaneous Complications

45 Fatigue

46 Caring for Patients at the End of Life



Section C. Local Effects of Cancer and Its Metastasis

47 Acute Abdomen, Bowel Obstruction, and Fistula

48 Superior Vena Cava Syndrome

49 Spinal Cord Compression

50 Brain Metastases and Neoplastic Meningitis

51 Bone Metastases

52 Lung Metastases

53 Liver Metastases

54 Effusions



Section D. Complications of Therapy

55 Rehabilitation for Individuals with Cancer

56 Survivorship

57 Neurologic Complications

58 Pulmonary Complications of Anticancer Treatment

59 Cardiac Effects of Cancer Therapy

60 Reproductive Complications

61 Endocrine Complications

62 Second Malignant Neoplasms



Section E. Special Populations

63 Cancer in the Elderly: Biology, Prevention, and Treatment

64 Special Issues in Pregnancy

65 HIV-Associated Malignancies



Part III: Specific Malignancies

66 Cancer of the Central Nervous System

66 Cancer of the Central Nervous System

67 Eye, Orbit, and Adnexal Structures

68 Cancer of the Head and Neck

69 Melanoma

70 Nonmelanoma Skin Cancers: Basal Cell and Squamous Cell Carcinomas

71 Cancer of the Endocrine System

72 Cancer of the Lung: Non-Small Cell Lung Cancer and Small Cell Lung Cancer

73 Tumors of the Pleura and Mediastinum

74 Cancer of the Esophagus and Gastroesophageal Junction

75 Cancer of the Stomach

76 Cancer of the Small Bowel

77 Colon Cancer

78 Cancer of the Rectum

79 Cancer of the Anal Canal

80 Liver and Bile Duct Cancer

81 Carcinoma of the Pancreas

82 Cancer of the Kidney

83 Carcinoma of the Bladder

84 Prostate Cancer

85 Cancer of the Penis

86 Testicular Cancer

87 Cancers of the Cervix, Vulva, and Vagina

88 Cancer of the Endometrium

89 Ovaries and Fallopian Tubes

90 Gestational Trophoblastic Disease

91 Cancer of the Breast

92 Sarcomas of Bone

93 Sarcomas of Soft Tissue

94 Carcinoma of Unknown Primary

95 Pediatric Solid Tumors

96 Childhood Leukemia

97 Childhood Lymphoma

98 Acute Myeloid and Lymphocytic Leukemia in Adults

99 Myelodysplastic Syndromes

100 Myeloproliferative Disorders

101 Chronic Myeloid Leukemia

102 Chronic Lymphoid Leukemias

103 Hairy Cell Leukemia

104 Multiple Myeloma and Related Disorders

105 Hodgkin's Lymphoma 106

106 Non-Hodgkin's Lymphoma

107 Cutaneous T-Cell Lymphoma and Cutaneous B-Cell Lymphoma

108 Adult T-Cell Leukemia-Lymphoma