Feigin and Cherry's Textbook of Pediatric Infectious Diseases helps you put the very latest knowledge to work for your young patients with unparalleled coverage of everything from epidemiology, public health, and preventive medicine through clinical manifestations, diagnosis, treatment, and much more. Ideal for all physicians, whether in an office or hospital setting, Feigin and Cherry’s equips you with trusted answers to your most challenging clinical infectious disease questions.



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Implement the latest knowledge on cutting-edge topics with coverage of new developments in novel viral infections, expanding bacterial resistance, evaluation of immunocompromised hosts, invasive fungal infections, device-related infections, global travel medicine, neglected tropical diseases, and much more.
Stay at the forefront of the pediatric infectious disease field through continuing and extensive updates on antibiotic resistance, novel therapeutics, and new molecular techniques in laboratory diagnosis.
Recognize under which circumstances the use of diagnostic imaging is most appropriate and know the efficient diagnosis for infectious diseases.
Key Features
Meet your most difficult clinical challenges in pediatric infectious disease, including today’s more aggressive infectious and resistant strains as well as emerging and re-emerging diseases, with unmatched, comprehensive coverage of immunology, epidemiology, public health, preventive medicine, clinical manifestations, diagnosis, treatment, and much more.
Find the answers you need quickly thanks to an organization both by organ system and by etiologic microorganism, allowing you to easily approach any topic from either direction.
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Part I Host Parasite Relationships an dthe Pathogenesis of Infectious Diseases


1. Molecular Determinants of Microbial Pathogenesis

2. Normal and Impaired Immunologic Responses to Infection

3. Metabolic Response and Nutritional Aspects of the Host to Infections and Interaction of Infection and Nutrition

4. Fever: Pathogenesis and Treatment

5. The Human Microbiome

6. Epidemiology and Biostatistics of Infectious Diseases


Part II Infection of Specific Organ Systems


Section I Upper Respiratory Tract Infections


7. The Common Cold

8. Infections of the Oral Cavity

9. Pharyngitis (Pharyngitis, Tonsillitis, Tonsillopharyngitis, and Nasopharyngitis)

10. Uvulitis

11. Peritonsillar, Retropharyngeal and Parapharyngeal Abscesses

12. Cervical Lymphadenitis

13. Parotitis

14. Sinusitis

15. Otitis Externa

16. Otitis Media

17. Mastoiditis

18. Epiglottitis (Supraglottitis) Croup (Laryngitis, Laryngotracheitis, Spasmodic Croup, Laryngotracheobronchitis, Bacterial Tracheitis, and Laryngotracheobronchopneumonitis)

Section II Lower Respiratory Tract Infections


19. Acute Bronchitis

20. Chronic Bronchitis

21. Bronchiolitis and Infectious Asthma

22. Community Acquired Pneumonias

23. Children's Interstitial Lung Disease and Hypersensitivity Pneumonitis

24. Pleural Effusions and Empyema, Lung Abscesses and Complications of Pneumonia

25. Cystic Fibrosis


Section III: Infections of the Heart


26. Infective Endocarditis

27. Infectious Pericarditis

28. Myocarditis

29. Acute Rheumatic Fever

30. Mediastinitis






Section IV: Central Nervous System Infections


31. Bacterial Meningitis Beyond the Neonatal Period

32. Brain abscesses Parameningeal Infections

33. Fungal Meningitis

34. Eosinophilic Meningitis

35. Aseptic Meningitis and Viral Meningitis

36. Encephalitis and Meningoencephalitis

37. Parainfections and Postinfectious Disorders of the Nervous System


37a. Parainfections and Postinfections Demyelinating Disorders of the Central Nervous System

37b. Infection-Associated Myelitis and Meylopathies of the Spinal Cord and . Parainfections and Postinfections Disorders of the Peripheral Nervous System


Section V Genitourinary Tract Infections


38. Urethritis

39. Cystitis and Pyelonephritis

40. Renal Abscess

41. Prostatitis

42. Genital Infections

Section VI Gastrointestinal Tract Infections


43. Esophagitis

44. Gastrointestinal Tract Infections and Food Poisoning

45. Antibiotic Associated Colitis

46. Whipple Disease

Section VII Liver Disease

47. Hepatitis

48. Cholangitis and Cholecystitis

49. Pyogenic Liver Abscess

50. Reye Syndrome


Section VIII Other Intra-Abdominal Infections


51. Appendicitis and Pelvic Abscess

52. Pancreatitis

53. Peritonitis and Intraabdominal Abscess

54. Retroperitoneal Infections


Section IX Musculoskeletal Infections


55. Osteomyelitis

56. Septic Arthritis

57. Bacterial Myositis and Pyomyositis


Section X Skin Infections


58. Cutaneous Manifestatiions of Systemic Infections

59. Roseola Infantum (Exanthem Subitum)

60. Skin Infections


Section XI Ocular Infectious Diseases


61. Ocular Infectious Diseases


Section XII Systemic Infectious Diseases


62. Bacteremia and Septic Shock

63. Fever Without Source and Fever of Unknown Origin

64. Toxic Shock Syndrome

65. Acute Respiratory Distress Syndrome in Children


Section XIII Infections of the Fetus and Newborn


66. Approach to the Infections in the Fetus and Neonate (Fetal Congenital and Neonate)


Section XIV Infections of the Compromised Host


67. Primary Immunodeficiencies

68. The Febril Neutropenic Patient

69. Opportunistic Infections In Hematopoietic Stem Cell Transplantation



70. Infections in Pediatric Heart Transplantaton

71. Infections in Pediatric Lung Transplantation

72. opportunistic Infections in Liver and Intestinal Transplantation

73. Opportunistic Infections in Kidney Transplantation

74. Infections Related to Prosthetic or Artificial Devices (Includes Shunt Infections)

75. Infections Related to Craniofacial Surgical Procedures

76. Infections in Burn Patients


Section XV Unclassified Infectious Diseases


77. Kawasaki Disease

78. Chronic Fatigue Syndrome


Part III Infections with Specific Microorganisms


Section XVI Bacterial Infections


79. Nomenclature for Aerobic and Anaerobic Bacteria




Subsection 1 Gram Positive Cocci


80. Staphylococcus Aureus Infections (Coagulase-Positive Staphylococci)

81. Coagulase -Negative Staphylococcal Infections

82. Group A, Group C and Group G Beta - Hemolytic Streptococcal Infection

83. Group B Streptococcal Infections

84. Enterococcal and Viridans Streptococcal Infections

85. Pneumococcal Infections

86. Miscellaneous Gram Positive Cocci


Subsection 2 Gram Negative Cocci


87. Moraxella Catarrhalis

88. Meningococcal Infections

89. Gonococcal Infections


Subsection 3 Gram Positive Bacilli


90. Diptheria

91. Anthrax

92. Bacillus Cereus

93. Arcanobacterium Haemolyticum

94. Erysipelothrix Rhusiopathiae

95. Listeriosis

96. Tuberculosis

97. Other Mycobacteria

98. Leprosy and Buruli Ulcer: The Major Cutaneous Mycobacterioses

99. Nocardia

100. Corynebacterium and Rhodococcus


Subsection 4 Gram Negative Bacilli


101. Citrobacter

102. Enterobacter

103. Escherichia Coli

104. Diarrhea-Causing and Dysentery-Causing Escherichia coli

105. Klebsiella

106. Morganella Morganii

107. Proteus

108. Providencia

109. Shigella

110. Serratia

111. Salmonella

112. Plague (Yersinia Species)

113. Other Yersinia Species

114. Edwardsiella Tarda, Hafnia Alvei, Pantoea Agglemerans

115. Aeromonas

116. Pasteurella Multocida

117. Cholera

118. Vibrio Parahaemolyticus

119. Vibrio Vulnificus

120. Chromobacterium

121. Acinetobacter

122. Achromobacter

123. Eikenella Corrodens

124. Elizabethkingia and Chryseobacterium Species

125. Pseudomonas and Related Genera

126. Stenotrophomonas (Xanthomonas) Maltophilia


Subsection 5 Gram Negative Coccobacilli


127. Actinobacillus Actinomycetemcomitans

128. Brucellosis

129. Pertussis and Other Bordetella Infections

130. Calymmatobacterium Granulomatis

131. Campylobacter Jejuni

132. Tularemia

133. Haemophilus Influenzae

134. Other Haemophilus Species Aphrophilus, Ducreyi, Haemolyticus, Influenzae Biogroup Aegyptius, Parahaemolyticus and Parainfluenzae

135. Helicobacter Pylori

136. Kingella Species

137. Legionella

138. Streptobacillus Moniliformis (Rat Bite Fever)

139. Bartonella

Subsection 6 Treponemataceae


140. Borrelia (Relapsing Fever and Lyme Disease)

141. Leptospirosis

142. Spirillum Minus (Rat Bite Fever)

143. Syphylis

144. Nonvenereal Treponematoses


Subsection 7 Anaerobic Bacteria


145. Clostridial Intoxications and Infection

146. Infant Botulism

147. Tetanus

148. Actinomycosis

149. Bacteroides Fusobacterium and Prevobella


Section XVII: Viral Infections


150. Classification and Nomenclature of Viruses


DNA Viruses - Subsection 1 Parvoviridae


151. Human Parvovirus

152. Human Bocaviruses


DNA Viruses - Subsection 2 Polyomaviridae


153. Human Polyomaviruses

154. Human Papillomaviruses


DNA Viruses - Subsection 3 Adenovirses


155. Adneoviruses


DNA Viruses - Subsection 4 Hepatoviridae


156. Hepatitis B and D Viruses


DNA Viruses - Subsection 5 Herpesvididae


157. Herpes Simplex Viruses 1 and 2

158. cytomegalovirus

159. Epstein Barr Virus

160. Human Heerpesviruses 6,7 and 8

161. Varicella Zoster Virus




DNA Viruses - Subsection 6 Poxviridae

162. Smallpox (Variola Virus)

163. Monkey Pox and Other Pox Viruses


164. Mimiviruses

RNA Viruses - Subsection 1 Picornaviridae

165. Enteroviruses and parechoviruses

166. Rhinoviruses

167. Hepatitis A Virus

RNA Viruses - Subsection 2 Caliciviridae

168. Caliciviruses

169. Hepatitis E Virus

RNA Viruses - Subsection 3 Reoviridae

170. Reoviruses

171. Orbiviruses, Coltiviruses, and Seadornaviruses

172. Rotaviruses


RNA Viruses - Subsection 4 Togaviridae

173. Rubella Virus

174. Alphaviruses

174-A: Eastern Equine Encephalitis

174-B: Western Equine Encephalitis



174-C: Venezuelan Equine Encephalitis

174-D: Chikungunya

174-E: Ross River Virus Arthritis

174-F: Other Alphaviral Infections


Subsection 5 Flaviviridae


175. Flaviviruses

175-A: St. Louis Encephalitis

175-B West Nile Virus

175-C: Yellow Fever

175-D: Dengue and Dengue Hemorrhagic Fever

175-E: Japanese Encephalitis

175-F: Murray Valley Encephalitis

175-G: Tick-Borne Encephalitis

175-H: Other Flaviviral Infections

176. Hepatitis C Virus


Subsection 6 Orthomyxoviridae

177. Influenza Viruses


Subsection 7 Paramyxoviridae


178. Parainfluenza Viruses

179. Measles Virus

180. Mumps Virus

181. Respiratory Syncytial Virus

182. Human Metapneumovirus




Subsection 8 Rhabdoviridae


183. Rabies Virus

Subsection 9: Arenaviridae and Filoviridae

184. Lymphocytic Choriomeningitis Virus Infection

185. Arenaviral Hemorrhagic Fevers

186. Filoviral Hemorrhagic Fever: Marburg and Ebola Virus


Subsection 10: Coronaviridae and Toroviridae


187. Coronaviruses and Toroviruses, Including Severe Acute Respiratory Syndrome




Subsection 11: Bunyaviridae


188. Hantaviruses

189. La Crosse Encephalitis and Other California Serogroup Viruses

190. Other Bunyaviridae

190-A: Rift Valley Fever

190-B: Crimean-Congo Hemorrhagic Fever

190-C: Phlebotomus Fever (Sandfly Fever)

190-D: Oropouche Fever

190-E: Toscana Virus


Subsection 12: Retroviridae


191. Human Retroviruses - this is not a chapter it is a heading for the 2 chapters below



191-A: Oncoviruses (Human T-Cell Lymphotropic Viruses) and Lentiviruses (human Immunodeficiency Virus Type 2)

191-B:Human Immunodeficiency Virus Type 1 and Acquired Immunodeficiency Syndrome



Subsection 13: Prion Related Diseases


192. Transmissible Spongiform Encephalopathies (Creutzfeldt-Jakob Disease, Gerstmann-Straussler-Scheinkeer Disease, Kuru, Fatal Familial Insomnia New Variant Creutzfeldt-Jakob Disease, Sporadic Fatal Insomnia)


Section XVIII Chlamydia


193. Chlamydia Infections


Section XIX Rickettsial Diseases


194. Rickettsial and Ehrlichial Diseases


Section XX Mycoplasma


195. Mycoplasma and Ureaplasma Infections


Section XXI Fungal Diseases


196. Classification of Fungi



197. Aspergillosis

198. Blastomycosis

199. Candidiasis

200. Coccidioidomycosis



201. Paracoccidioidomycosis

202. Cryptococcosis



203. Histoplasmosis

204. Sporotrichosis

205. Zygomycosis



206. Scedosporiosis and Fusariosis

207. Miscellaneous Mycoses




Section XXII Parasitic Diseases


208. Classification and Nomenclature of Human Parasites


Subsection 1 Protozoa A. Amebae


209. Amebiasis

210. Blastocystis Hominis Infection

211. Entamoeba Coli Infection

212. Giardiasis

213. Dientamoeba Fragilis Infections

214. Trichomonas Infections

215. Balantidium Coli Infection

216. Cryptosporidiosis



217. Cyclosporiasis, Isosporiasis and Microsporidiosis



218. Babesiosis

219. Malaria



220. Leishmaniasis

221. Trypanosomiasis

222. Naegleria, Acanthamoeba, and Balamuthia

223. Toxoplasmosis

224. Pneumocystis Pneumonia




Subsection 2: Nematodes


225. Parasitic Nematode Infections


Subsection 3: Cestodes


226. Cestodes



Subsection 4: Trematode


227. Trematode Foodborne Infections

228. Schistosomiasis


Subsection 5: Arthropods


229. Arthropods and Scabiest

Section XXIII Global Health


230. Global Health

231. International Travel Issues for Children

232. Infectious Disease Considerations in International Adoptees and Refugees


Part IV Therapeutics


233. Antibiotic Resistance

234. The Pharmacokinetic-Pharmacodynamic Interface: Determinants of Anti-Infective Drug Action and Efficacy in Pediatrics



235. Antibacterial Therapeutic Agents



236. Antimicrobial Prophylaxis



237. Outpatient Intravenous Antimicorbial Therapy for Serious Infections

238. Antiviral Agents

239. Antifungal Agents

240. Drugs for Parasitic Infections

241. Immunomodulating Agents

242. Probiotics


Part V Prevention of Infectious Diseases


243. Health Care Associated Infections and Precautions

244. Active Immunizing Agents

245. Passive Immunization


Section XXIII Other Preventive Considerations


246. Public Health Aspects of Infectious Disease Control



247. Infections in Daycare Environments

248. Human Bites and Animal Bites

249. Bioterrorism


Part VI Approach to the Laboratory Diagnosis of Infectious Diseases


250. Bacterial Laboratory Diagnosis



251. Fungal Laboratory Analysis: Specimen Collection, Direct, Detection and Culture



252. Viral Laboratory Diagnosis



253. Parasitic Laboratory Diagnosis