Marks’ Basic Medical Biochemistry takes a patient-oriented approach that links biochemistry to physiology and pathophysiology, allowing students to apply fundamental concepts to the practice of medicine—from diagnosing patients to recommending effective treatments. Intuitively organized chapters center on hypothetical patient vignettes and helpful icons allow for smooth navigation, making complex concepts easier to grasp!


Access additional resources online with purchase of text! Instructors receive access to a dedicated Image Bank as well as all student features, which include fully searchable eBook; animations depicting 9 key biochemical concepts; interactive question bank with more than 450 USMLE questions and complete rationales; full patient summaries for each patient discussed in the text; comprehensive list of disorders covered in the text, with relevant web links; and suggested readings for further exploration.

Section One: FUEL METABOLISM 1: Metabolic Fuels and Dietary Components 2: The Fed or Absorptive State 3: Fasting Section Two : CHEMICAL AND BIOLOGICAL FOUNDATIONS OF BIOCHEMISTRY 4: Water, Acids, Bases, and Buffers 5: Structures of the Major Compounds of the Body 6: Amino Acids in Proteins 7: Structure-Function Relationships in Proteins 8: Enzymes as Catalysts 9: Regulation of Enzymes 10: Relationship between Cell Biology and Biochemistry 11: Cell Signaling by Chemical Messengers Section Three: GENE EXPRESSION AND THE SYNTHESIS OF PROTEINS 12: Structure of the Nucleic Acids 13: Synthesis of DNA 14: Transcription: Synthesis of RNA 15: Translation: Synthesis of Proteins 16: Regulation of Gene Expression 17: Use of Recombinant DNA Techniques in Medicine 18: The Molecular Biology of Cancer Section Four: FUEL OXIDATION AND THE GENERATION OF ATP 19: Cellular Bioenergetics: ATP and O2 20: Tricarboxylic Acid Cycle 21: Oxidative Phosphorylation and Mitochondrial Function 22: Generation of Adenosine Triphosphate from Glucose: Glycosis 23: Oxidation of Fatty Acids and Ketone Bodies 24: Oxygen Toxicity and Free Radical Injury 25: Metabolism of Ethanol Section Five: CARBOHYDRATE METABOLISM 26: Basic Concepts in the Regulation of Fuel Metabolism by Insulin, Glucagon, and Other Hormones 27: Digestion, Absorption, and Transport of Carbohydrates 28: Formation and Degradation of Glycogen 29: Pathways of Sugar Metabolism: Pentose Phosphate Pathway, Fructose, and Galactose Metabolism 30: Synthesis of Glycosides, Lactose, Glycoproteins, and Glycolipids 31: Gluconeogenesis and Maintenance of Blood Glucose Levels Section Six: LIPID METABOLISM 32: Digestion and Transport of Dietary Lipids 33: Synthesis of Fatty Acids, Triacylglycerols, and the Major Membrane Lipids 34: Cholesterol Absorption, Synthesis, Metabolism, and Fate 35: Metabolism of the Eicosanoids 36: Integration of Carbohydrate and Lipid Metabolism Section Seven: NITROGEN METABOLISM 37: Protein Digestion and Amino Acid Absorption 38: Fate of Amino Acid Nitrogen: Urea Cycle 39: Synthesis and Degradation of Amino Acids 40: Tetrahydrofolate, Vitamin B12, and S-Adenosylmethionine 41: Purine and Pyrimidine Metabolism 42: Intertissue Relationships in the Metabolism of Amino Acids Section Eight: TISSUE METABOLISM 43: Actions of Hormones That Regulate Fuel Metabolism44: The Biochemistry of the Erythrocyte and Other Blood Cells 45: Blood Plasma Proteins, Coagulation and Fibrinolysis 46: Liver Metabolism 47: Metabolism of Muscle at Rest and During Exercise 48: Metabolism of the Nervous System 49: The Extracellular Matrix and Connective Tissue Appendix: Answers to Review Questions Index