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Part I: Understanding, Controlling, and Preventing Infectious Diseases
A. Epidemiology and Control of Infectious Diseases
1 Principles of Epidemiology and Public Health
2 Pediatric Infection Prevention and Control
3 Infections Associated with Group Childcare
4 Infectious Diseases in Refugee and Internationally Adopted Children
B. Prevention of Infectious Diseases
5 Passive Immunization
6 Active Immunization
7 Chemoprophylaxis
8 Protection of Travelers
C. Host Defenses against Infectious Diseases
9 Immunologic Development and Susceptibility to Infection
10 Fever and the Inflammatory Response
Part II: Clinical Syndromes and Cardinal Features of Infectious Diseases: Approach to Diagnosis and Initial Management
A. Septicemia, Toxin- and Inflammation-Mediated Syndromes
11 The Systemic Inflammatory Response Syndrome (SIRS), Sepsis, and Septic Shock
12 Hemophagocytic Lymphohistiocytosis and Macrophage Activation Syndrome
B. Cardinal Symptom Complexes
13 Mucocutaneous Symptom Complexes
14 Fever without Localizing Signs
15 Prolonged, Recurrent and Periodic Fever Syndromes
16 Lymphatic System and Generalized Lymphadenopathy
17 Cervical Lymphadenitis and Neck Infections
18 Mediastinal and Hilar Lymphadenopathy
19 Abdominal and Retroperitoneal Lymphadenopathy
20 Localized Lymphadenitis, Lymphadenopathy, and Lymphangitis
21 Respiratory Tract Symptom Complexes
22 Abdominal Symptom Complexes
23 Neurologic Symptom Complexes
24 Musculoskeletal Symptom Complexes
C. Oral Infections and Upper and Middle Respiratory Tract Infections
25 Infections of the Oral Cavity
26 The Common Cold
27 Pharyngitis
28 Infections Related to the Upper and Middle Airways
29 Otitis Media
30 Otitis Externa and Necrotizing Otitis Externa
31 Mastoiditis
32 Sinusitis
D. Lower Respiratory Tract Infections
33 Bronchiolitis
34 Acute Pneumonia and Its Complications
35 Persistent and Recurrent Pneumonia
36 Pneumonia in the Immunocompromised Host
E. Cardiac and Vascular Infections
37 Endocarditis and Other Intravascular Infections
38 Myocarditis
39 Pericarditis
F. Central Nervous System Infections
40 Acute Bacterial Meningitis beyond the Neonatal Period
41 Chronic Meningitis
42 Recurrent Meningitis
43 Aseptic and Viral Meningitis
44 Encephalitis
45 Para- and Postinfectious Neurologic Syndromes
46 Focal Suppurative Infections of the Nervous System
47 Eosinophilic Meningitis
48 Prion Diseases
G. Genitourinary Tract Infections
49 Urinary Tract Infections
50 Renal Abscess and Other Complex Renal Infections
51 Sexually Transmitted Infection Syndromes
52 Skin and Mucous Membrane Infections and Inguinal Lymphadenopathy
53 Urethritis, Vulvovaginitis, and Cervicitis
54 Pelvic Inflammatory Disease
55 Epididymitis, Orchitis, and Prostatitis
56 Infectious Diseases in Child Abuse
H. Gastrointestinal Tract Infections and Intoxications
57 Approach to the Diagnosis and Management of Gastrointestinal Tract Infections
58 Viral Gastroenteritis
59 Inflammatory Enteritis
60 Necrotizing Enterocolitis
61 Enteric Diseases Transmitted through Food, Water, and Zoonotic Exposures
I. Intra-Abdominal Infections
62 Acute Hepatitis
63 Chronic Hepatitis
64 Granulomatous Hepatitis
65 Acute Pancreatitis
66 Cholecystitis and Cholangitis
67 Peritonitis
68 Appendicitis
69 Intra-Abdominal, Visceral, and Retroperitoneal Abscesses
J. Skin and Soft-Tissue Infections
70 Superficial Bacterial Skin Infections and Cellulitis
71 Erythematous Macules and Papules
72 Vesicles and Bullae
73 Purpura
74 Urticaria and Erythema Multiforme
75 Papules, Nodules, and Ulcers
76 Subcutaneous Tissue Infections and Abscesses
77 Myositis, Pyomyositis, and Necrotizing Fasciitis
K. Bone and Joint Infections
78 Osteomyelitis
79 Infectious and Inflammatory Arthritis
80 Diskitis
81 Transient Synovitis
L. Eye Infections
82 Conjunctivitis in the Neonatal Period (Ophthalmia Neonatorum)
83 Conjunctivitis beyond the Neonatal Period
84 Infective Keratitis
85 Uveitis, Retinitis, and Chorioretinitis
86 Endophthalmitis
87 Periorbital and Orbital Infections
M. Infections Related to Trauma
88 Infection following Trauma
89 Infection following Burns
90 Infection following Bites
91 Infections Related to Pets and Exotic Animals
92 Tickborne Infections
N. Infections of the Fetus and Newborn
93 Clinical Approach to the Infected Neonate
94 Bacterial Infections in the Neonate
95 Viral Infections in the Fetus and Neonate
96 Hospital-Associated Infections in the Neonate
O. Infections and Transplantation
97 Infections in Solid Organ Transplant Recipients
98 Infections in Hematopoietic Stem Cell Transplant Recipients
P. Infections and Cancer
99 Fever and Granulocytopenia
100 Infections in Children with Cancer
Q. Infections Associated with Hospitalization and Medical Devices
101 Healthcare-Associated Infections
102 Clinical Syndromes of Device-Associated Infections
R. Infections in Patients with Deficient Defenses
103 Evaluation of the Child with Suspected Immunodeficiency
104 Infectious Complications of Antibody Deficiency
105 Infectious Complications of Complement Deficiencies
106 Infectious Complications of Dysfunction or Deficiency of Polymorphonuclear and Mononuclear Phagocytes
107 Infectious Complications of Cell-Mediated Immunity Other Than AIDS: Primary Immunodeficiencies
108 Infectious Complications in Special Hosts
S. Human Immunodeficiency Virus and the Acquired Immunodeficiency Syndrome
109 Epidemiology and Prevention of HIV Infection in Children and Adolescents
110 Immunopathogenesis of HIV-1 Infection
111 Diagnosis and Clinical Manifestations of HIV Infection
112 Infectious Complications of HIV Infection
113 Management of HIV Infection
Part III: Etiologic Agents of Infectious Diseases
A. Bacteria
114 Classification of Bacteria
Gram-Positive Cocci
115 Staphylococcus aureus
116 Staphylococcus epidermidis and Other Coagulase- Negative Staphylococci
117 Classification of Streptococci
118 Streptococcus pyogenes (Group A Streptococcus)
119 Streptococcus agalactiae (Group B Streptococcus)
120 Enterococcus Species
121 Viridans Streptococci, Abiotrophia and Granulicatella Species, and Streptococcus bovis
122 Groups C and G Streptococci
123 Streptococcus pneumoniae
124 Other Gram-Positive, Catalase-Negative Cocci
Gram-Negative Cocci
125 Neisseria meningitidis
126 Neisseria gonorrhoeae
127 Other Neisseria Species
Gram-Positive Bacilli
128 Archanobacterium haemolyticum
129 Bacillus Species (Anthrax)
130 Corynebacterium diphtheriae
131 Other Corynebacteria
132 Listeria monocytogenes
133 Other Gram-Positive Bacilli
134 Mycobacterium tuberculosis
135 Mycobacterium Species Non-tuberculosis
136 Nocardia Species
Enterobacteriaceae: Gram-Negative Bacilli
137 Escherichia coli
138 Klebsiella and Raoultella Species
139 Klebsiella (Calymmatobacterium) granulomatis (Granuloma Inguinale)
140 Enterobacter, Cronobacter, and Pantoea Species
141 Citrobacter Species
142 Less Commonly Encountered Enterobacteriaceae
143 Plesiomonas shigelloides
144 Proteus, Providencia, and Morganella Species
145 Serratia Species
146 Salmonella Species
147 Shigella Species
148 Yersinia Species
Nonenterobacteriaceae: Gram-Negative Bacilli
149 Acinetobacter Species
150 Aeromonas Species
151 Less Commonly Encountered Nonenteric Gram-Negative Bacilli
152 Eikenella, Pasteurella, and Chromobacterium Species
153 Moraxella and Psychrobacter Species
154 Pseudomonas Species and Related Organisms
155 Pseudomonas aeruginosa
156 Burkholderia cepacia Complex and Other Burkholderia Species
157 Stenotrophomonas maltophilia
158 Vibrio cholerae (Cholera)
159 Other Vibrio Species
Gram-Negative Coccobacilli
160 Bartonella Species (Cat-Scratch Disease)
161 Brucella Species (Brucellosis)
162 Bordetella pertussis (Pertussis) and Other Bordetella Species
163 Campylobacter jejuni and Campylobacter coli
164 Other Campylobacter Species
165 Capnocytophaga Species
166 Chlamydophila (Chlamydia) pneumoniae
167 Chlamydia trachomatis
168 Chlamydophila (Chlamydia) psittaci (Psittacosis)
169 Coxiella burnetii (Q fever)
170 Ehrlichia and Anaplasma Species (Ehrlichiosis and Anaplasmosis)
171 Francisella tularensis (Tularemia)
172 Haemophilus influenzae
173 Other Haemophilus Species
174 Helicobacter pylori
175 Other Gastric and Enterohepatic Helicobacter Species
176 Kingella Species
177 Legionella Species
178 Rickettsia rickettsii (Rocky Mountain Spotted Fever)
179 Other Rickettsia Species
180 Streptobacillus moniliformis (Rat-Bite Fever)
181 Other Gram-Negative Coccobacilli
Treponemataceae (Spiral Organisms)
182 Treponema pallidum (Syphilis)
183 Other Treponema Species
184 Leptospira Species (Leptospirosis)
185 Borrelia burgdorferi (Lyme Disease)
186 Other Borrelia Species and Spirillum minus
Anaerobic Bacteria
187 Anaerobic Bacteria: Classification, Normal Flora, and Clinical Concepts
188 Clostridium tetani (Tetanus)
189 Clostridium botulinum (Botulism)
190 Clostridium difficile
191 Other Clostridium Species
192 Bacteroides and Prevotella Species and Other Gram-Negative Bacilli
193 Fusobacterium Species
194 Anaerobic Cocci
195 Anaerobic Gram-Positive, Nonsporulating Bacilli (including Actinomycosis)
Mycoplasma
196 Mycoplasma pneumoniae
197 Other Mycoplasma Species
198 Ureaplasma urealyticum
Diseases of Possible Infectious or Unknown Etiology
199 Kawasaki Disease
200 Chronic Fatigue Syndrome
B. Viruses
201 Classification of Human Viruses
DNA Viruses: Poxviridae
202 Poxviridae
DNA Viruses: Herpesviridae
203 Introduction to Herpesviridae
204 Herpes Simplex Virus
205 Varicella-Zoster Virus
206 Cytomegalovirus
207 Human Herpesviruses 6 and 7 (Roseola, Exanthem Subitum)
208 Epstein-Barr Virus (Mononucleosis and Lymphoproliferative Disorders)
209 Human Herpesvirus 8 (Kaposi Sarcoma- Associated Herpesvirus)
DNA Viruses: Adenoviridae
210 Adenoviruses
DNA Viruses: Papovaviridae
211 Human Papillomaviruses
212 BK, JC, and Other Human Polyomaviruses
DNA Viruses: Hepadnaviridae
213 Hepatitis B and Hepatitis D Viruses
DNA Viruses: Parvoviridae
214 Human Parvoviruses
RNA Viruses: Reoviridae
215 Coltivirus (Colorado Tick Fever
216 Rotaviruses
RNA Viruses: Togaviridae, Flaviviridae, and Bunyaviridae
217 Togaviridae: Alphaviruses
218 Flaviviruses
219 Bunyaviruses
220 Hepatitis C Virus
221 Rubella Virus
RNA Viruses: Coronaviridae
222 Human Coronaviruses
RNA Viruses: Paramyxoviridae
223 Parainfluenza Viruses
224 Mumps Virus
225 Respiratory Syncytial Virus
226 Human Metapneumovirus
227 Rubeola Virus (Measles and Subacute
Sclerosing Panencephalitis)
RNA Viruses: Rhabdoviridae
228 Rabies Virus
RNA Viruses: Orthomyxoviridae
229 Influenza Viruses
RNA Viruses: Arenaviridae and Filoviridae
230 Filoviruses and Arenaviruses
RNA Viruses: Retroviridae
231 Introduction to Retroviridae
232 Human T-Cell Lymphotropic Viruses
233 Human Immunodeficiency Viruses
RNA Viruses: Picornaviridae
234 Introduction to Picornaviridae
235 Polioviruses
236 Enteroviruses and Parechoviruses
237 Hepatitis A Virus
238 Rhinoviruses
RNA Viruses: Caliciviridae
239 Caliciviruses
240 Astroviruses
241 Hepatitis E Virus and Other Newly Identified Viruses
C. Fungi
242 Classification of Fungi
243 Candida Species
244 Aspergillus Species
245 Agents of Hyalohyphomycosis and Phaeohyphomycosis
246 Agents of Mucormycosis (Zygomycosis)
247 Malassezia Species
248 Sporothrix schenckii (Sporotrichosis)
249 Cryptococcus Species
250 Histoplasma capsulatum (Histoplasmosis)
251 Pneumocystis jirovecii
252 Blastomyces dermatitidis (Blastomycosis)
253 Coccidioides immitis and Coccidioides posadasii (Coccidiomycosis)
254 Dermatophytes and Other Superficial Fungi
255 Agents of Eumycotic Mycetoma: Pseudallescheria boydii (Anamorph Scedosporium apiospermum)
D. Human Parasites and Vectors
256 Classification of Parasites
257 Ectoparasites (Lice and Scabies)
Protozoa
258 Babesia Species (Babesiosis)
259 Balantidium coli
260 Blastocystis Species
261 Cryptosporidium Species
262 Endolimax nana
263 Entamoeba histolytica (Amebiasis)
264 Other Entamoeba, Amebas, and Intestinal Flagellates
265 Giardia intestinalis (Giardiasis)
266 Cystoisospora (Isospora) and Cyclospora Species
267 Leishmania Species (Leishmaniasis)
268 Microsporidia
269 Naegleria fowleri
270 Acanthamoeba Species
271 Plasmodium Species (Malaria)
272 Sarcocystis Species
273 Toxoplasma gondii (Toxoplasmosis)
274 Trichomonas vaginalis
275 Trypanosoma Species (Trypanosomiasis)
Nematodes
276 Intestinal Nematodes
277 Tissue Nematodes
278 Blood and Tissue Nematodes (Filarial Worms)
Cestodes
279 Diphyllobothrium, Dipylidium, and Hymenolepis Species
280 Taenia solium, Taenia asiatica, and Taenia saginata (Taeniasis and Cysticercosis)
281 Echinococcus Species (Agents of Cystic, Alveolar, and Polycystic Echinococcosis)
282 Taenia (Multiceps) multiceps and Taenia serialis (Coenurosis)
Trematodes
283 Intestinal Trematodes
284 Clonorchis, Opisthorchis, Fasciola, and Paragonimus Species
285 Blood Trematodes (Schistosomiasis)
Part IV: Laboratory Diagnosis and Therapy of Infectious Diseases
A. The Clinician and the Laboratory
286 Laboratory Diagnosis of Infection
Due to Bacteria, Fungi, Parasites, and Rickettsiae
287 Laboratory Diagnosis of Infection Due to Viruses, Chlamydia, Chlamydophila, and Mycoplasma
288 Laboratory Manifestations of Infectious Diseases
B. Anti-Infective Therapy
289 Principles of Anti-Infective Therapy
290 Mechanisms and Detection of Antibiotic Resistance
291 Pharmacokinetic-Pharmacodynamic Basis of Optimal Antibiotic Therapy
292 Antimicrobial Agents
293 Antifungal Agents
294 Topical Antimicrobial Agents
295 Antiviral Agents
296 Antiparasitic Agents |
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