--- Description ---

Berne and Levy Physiology has long been respected for its scientifically rigorous approach and now includes major updates to bring you all of the latest knowledge in the field. Bruce M. Koeppen and Bruce A. Stanton present a honed and shortened edition that emphasizes the core information needed by students of physiology today and features a full-color design and artwork to enhance readability and enrich your comprehension of every concept. With access to the full contents online at Student Consult, this time-honored book delivers an in-depth understanding of physiology more powerfully and effectively than ever before.

--- Reviews ---

"This physiology textbook will continue to be one of the standards for medical education for the foreseeable future."—The Physiologist, review of the previous edition

--- Key Features ---

Describes all of the mechanisms that control and regulate bodily function using a clear and intuitive organ system-based approach.
Provides a rich understanding of the body's dynamic processes through key experimental observations and examples.
Includes Student Consult access to the complete and searchable contents of the book online, as well as relevant bonus content from other Student Consult titles, an image gallery, 10 physiology animations, and much more.

--- New to this Edition ---

Features updated coverage throughout to expand your understanding of the most current trends in physiology and medicine, including the latest cellular and molecular knowledge.
Includes shaded boxes that highlight and explain important clinical and molecular information.
Presents new section editors who ensure that you are getting the freshest, most clinically relevant information available today.
Summarizes need-to-know information in each chapter with Key Points sections.

--- Related Titles ---

Elsevier's Integrated Physiology : With STUDENT CONSULT Online Access
Medical Physiology, 2nd Edition : With STUDENT CONSULT Online Access
Problem-Based Physiology
Berne & Levy Principles of Physiology, 4th Edition : With STUDENT CONSULT Online Access

--- Author Information ---

By Bruce M. Koeppen, MD, PhD, Professor of Medicine & Physiology, Dean Academic Affairs & Education, University of Connecticut Health Center, Farmington, CT and Bruce A. Stanton, PhD, Professor of Physiology, Department of Physiology, Dartmouth Medical School, Hanover, NH

Section I: Cellular Physiology 1

Bruce M. Koeppen and Bruce A. Stanton

1. Principles of Cell Function 3

2. Homeostasis of Body Fluids 20

3. Signal Transduction, Membrane Receptors, Second Messengers,

and Regulation of Gene Expression 34


Section II: The Nervous System 51

Kalman Rubinson and Eric J. Lang

4. The Nervous System: Introduction to Cells and Systems 53

5. Generation and Conduction of Action Potentials 65

6. Synaptic Transmission 82

7. The Somatosensory System 105

8. The Special Senses 123

9. Organization of Motor Function 157

10. Higher Functions of the Nervous System 201

11. The Autonomic Nervous System and its Central Control 218


Section III: Muscle 231

James M. Watras

12. Skeletal Muscle Physiology 233

13. Cardiac Muscle 256

14. Smooth Muscle 268


Section IV: The Cardiovascular System 287

Achilles J. Pappano

15. Overview of Circulation 289

16. Elements of Cardiac Function 292

17. Properties of the Vasculature 330

18. Regulation of the Heart and Vasculature 370

19. Integrated Control of the Cardiovascular System 393


Section V: The Respiratory System 415

Michelle M. Cloutier and Roger S. Thrall

20. Structure and Function of the Respiratory System 417

21. Mechanical Properties of the Lung and Chest Wall: Static

and Dynamic 430

22. Ventilation (V), Perfusion (Q), and V/Q Relationships 444

23. Oxygen and Carbon Dioxide Transport 459

24. Control of Respiration 468

25. Nonrespiratory Functions of the Lung 477


Section VI: Gastrointestinal Physiology 485

Kim E. Barrett and Helen E. Raybould

26. Functional Anatomy and General Principles of Regulation

in the Gastrointestinal Tract 487

27. The Cephalic, Oral, and Esophageal Phases of the Integrated

Response to a Meal 496

28. The Gastric Phase of the Integrated Response to a Meal 504

29. The Small Intestinal Phase of the Integrated Response to a Meal 516

30. The Colonic Phase of the Integrated Response to a Meal 533

31. Transport and Metabolic Functions of the Liver 542


Section VII: The Renal System 555

Bruce A. Stanton and Bruce M. Koeppen

32. Elements of Renal Function 557

33. Solute and Water Transport along the Nephron:

Tubular Function 578

34. Control of Body Fluid Osmolality and Volume 594

35. Potassium, Calcium, and Phosphate Homeostasis 619

36. Role of the Kidneys in the Regulation of Acid-Base Balance 636


Section VIII: The Endocrine and Reproductive

Systems 651

Bruce A. White

37. Introduction to the Endocrine System 653

38. Hormonal Regulation of Energy Metabolism 664

39. Hormonal Regulation of Calcium and Phosphate Metabolism 696

40. The Hypothalamus and Pituitary Gland 706

41. The Thyroid Gland 725

42. The Adrenal Glands 738

43. The Male and Female Reproductive Systems 758


Index 799